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WebIt is no coincidence that most of these drugs are sold strictly on prescription. This therapy has not only contraindications, but also a limited effect. For example, they "don't work" in … WebSildenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Sildenafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow easily.

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