Manganese-based tumor immunotherapy
Web16. apr 2024. · Manganese-Based Nanoactivator Optimizes Cancer Immunotherapy via Enhancing Innate Immunity. Lin Hou * Lin Hou. School of Pharmaceutical Sciences, … Web01. mar 2024. · A completed phase 1 clinical trial with the combined regimen of Mn2+ and anti-PD-1 antibody showed promising efficacy, exhibiting type I IFN induction, manageable safety and revived responses to immunotherapy in most patients with advanced metastatic solid tumors. Expand
Manganese-based tumor immunotherapy
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Web13. apr 2024. · In recent years, the application of mRNA vaccine-based tumor immunotherapy invigorated anti-tumor therapy. However, the low efficiency of mRNA … Web17. avg 2024. · Hou, L. et al. Manganese-based nanoactivator optimizes cancer immunotherapy via enhancing innate immunity. ACS Nano 14 , 3927–3940 (2024). …
Web28. apr 2024. · Recent studies have revealed that manganese (Mn) can enhance cGAS and STING activation to viral infection. However, the role of Mn in antitumor immunity has not … Web10. apr 2024. · Image: Rapamycin was self-assembled into a water-soluble nanoparticle by BSA, and then loaded onto PCN-224. The [email protected]@HA was constructed with HA modification on the surface and then entered the tumor tissue through passive EPR targeting and active HA targeting. Under the action of 660 nm laser, rapamycin was …
Web19. sep 2024. · Manganese-based tumor immunotherapy. Ke Zhang, Ke Zhang. Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of … Web1 day ago · Immunotherapy has emerged to play a rapidly expanding role in the treatment of cancers. Currently, many clinical trials of therapeutic agents are on ongoing with …
Web20. apr 2024. · The limited clinical response and serious side effect have been challenging in cancer immunotherapy resulting from immunosuppressive tumor microenvironment …
WebAbout. Research Scientist with a demonstrated experience in designing and developing nano/micro particle based drug/ nucleic acid delivery systems for cancer/gene therapy. Familiar with particle ... gymnastics sec championshipsWeb19. sep 2024. · Abstract. As an essential micronutrient, manganese (Mn) participates in various physiological processes and plays important roles in host immune system, hematopoiesis, endocrine function, and oxidative … gymnastics seasonWeb06. apr 2024. · The main factors affecting the efficacy of immunotherapy include tumor antigens, their mutational loads, host immune-related genetic variants, tumor microenvironment, and gut microbiome. 47 Among them, the TME highly influences the development of tumors and treatment prognosis. 44, 48 In recent years, an increasing … bozeman snowmobiling toursWeb26. mar 2024. · Manganese‐Based Tumor Immunotherapy . 相关领域. 免疫疗法 ... Immunotherapy: Reshape the Tumor Immune Microenvironment; Manganese‐Based Tumor Immunotherapy; Metabolism heterogeneity in melanoma fuels deactivation of immunotherapy: Predict before protect gymnastics searcy arWeb15. jan 2024. · Next, we systematically reviewed the Mn2+-based strategies for tumor immunotherapy, which can be classified by the methods based on Mn2+ alone or Mn2+ combined with other therapeutic modalities. bozeman snow plowingWeb13. apr 2024. · Immune-checkpoint inhibitors show promising effects in the treatment of multiple tumor types. Biomarkers are biological indicators used to select patients for a systemic anticancer treatment, but ... bozeman snow reportWebCD8 + T cell-mediated cancer clearance is often suppressed by the interaction between inhibitory molecules like PD-1 and PD-L1, an interaction acts like brakes to prevent T cell … bozeman snow tubing