Stemness in cancer
網頁2024年4月14日 · Abstract. Cancer recurrence and metastasis are the primary reasons for treatment failure in late-stage oral cancer. Cancer stem cells are the root of cancer recurrence and metastasis. By using the microRNAome analysis of Taiwan OSCC cohort, we found miR-876-3p was highly correlated to OSCC recurrence. The precursor miR-876 … 網頁Targeting cancer stem cells: emerging role of Nanog transcription factor. Abstract: The involvement of stemness factors in cancer initiation and progression has drawn much …
Stemness in cancer
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網頁2024年1月5日 · Cancer stem cells (CSCs) are self-renewing cells that facilitate tumor initiation, promote metastasis, and enhance cancer therapy resistance. Transcriptomic … 網頁Abstact Accumulating lines of experimental evidence have revealed that hypoxia-inducible factors, HIF-1α and HIF-2α, are key regulators of the adaptation of cancer- and metastasis-initiating cells and their differentiated progenies to oxygen and nutrient deprivation ...
網頁Instead, cancer cells are highly plastic in term of stemness and CSCs and non-CSCs can interconvert into each other depending on the microenvironment. This model predicts the existence of cancer cells ranging from a pure CSC phenotype to pure non-CSC phenotype and that survival of a single cell can originate a new tumor. 網頁2016年9月9日 · Increased expression of galectin-3 was detected in advanced stages, compared to stage 1 or 2 in ovarian cancer patients, suggesting that galectin-3 supports stemness of these cells. Based on these results, we suggest that targeting galectin-3 may be a potent approach for improving ovarian cancer therapy.
網頁2024年7月21日 · BackgroundCancer stem cells (CSCs) have been proven to influence drug resistance, recurrence, and metastasis in tumors. Our study aimed to identify stemness … 網頁lncRNA DGCR5 Up-Regulates TGF-beta1, Increases Cancer Cell Stemness and Predicts Survival of Prostate Cancer Patients Bin Li,1 Zhirui Guo,2 Quan Liang,1 Huiling Zhou,3 Yanping Luo,4 Shuyun He,2 Zhe Lin1 1Department of Urology, The First Peoples’ Hospital of Foshan, Foshan City, Guangdong Province 528000, People’s Republic of China; …
網頁a newly identified driver of breast cancer stemness and metastasis. Using protein structure modeling and interface prediction-guided mutagenesis, we demonstrate that membrane CD81 interacts with CD44 through their extracellular regions in promoting ...
網頁2016年12月9日 · Stemness combines the ability of a cell to perpetuate its lineage, to give rise to differentiated cells, and to interact with its environment to maintain a balance between quiescence, proliferation, and regeneration. While adult Stem Cells display these … Trait Normal Stem Cells Cancer Stem Cells Niche element: mesenchymal cells … While adult Stem Cells display these properties when participating in tissue … For many types of cancer, CSCs are thought to be responsible for metastasis, … When you publish, edit, or peer review with a Hindawi journal, you become part of a … Publish with HindawiJoin our community of authors and benefit from: An easy-to-use … We may share your personal data as follows: Within Wiley. We may share … System with services The Phenom system and publisher services are designed to … We use cookies to ensure that you get the most out of our Site. Cookies are small … georgian stuffed eggplant recipe網頁Here, we report that PTPRU serves as a tumor suppressor that inhibits cancer stemness by attenuating Hippo/YAP signaling pathway. Methods: Primary cancer cells and cell line … christian mysteries網頁Abstract. The ability of cancers to grow indefinitely has fueled the idea that cancer and stem cells may have common underlying mechanisms. Detailed gene expression maps have … georgian style furniture網頁2024年4月4日 · Stemness of cancer cells is a key feature for cancer progression and in many cases the source of its survival [7–12]. Understanding the development and acquisition of resistance in cancer cells may therefore provide … christian mysteries and suspense for kindle網頁2024年11月18日 · Over the last decades, the cancer survival rate has increased due to personalized therapies, the discovery of targeted therapeutics and novel biological agents, and the application of palliative treatments. Despite these advances, tumor resistance to chemotherapy and radiation and rapid progression to metastatic disease are still seen in … georgian style fireplace surroundsObjective: Colon cancer stem-like cells (CSCs) are self-renewing and tumor-initiating. They are resistant to chemotherapy drugs, such as doxorubicin. The presence of this subpopulation leads to poor treatment outcomes, recurrence and metastasis in colon cancer. Therefore, current therapeutic strategies targeting stem cell self-renewal … georgian stores barrie網頁TY - JOUR T1 - Resveratrol Impedes the Stemness, Epithelial-Mesenchymal Transition, and Metabolic Reprogramming of Cancer Stem Cells in Nasopharyngeal Carcinoma through … christian mysteries fiction